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Liposarcoma classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2]

Overview

Liposarcoma may be classified into well-differentiated, de-differentiated, myxoid, round cell, or pleomorphic liposarcoma.

Classification

Liposarcoma is a type of soft tissue sarcoma, which accounts for approximately 20% of the mesenchymal malignancies. Liposarcomas may be classified into different subtypes, according to their histologic, cytogenetic, biologic, and molecular features. The World Health Organization proposed the following classification of liposarcomas:[1][2][3]

WHO Classification of Liposarcoma[3]
  • Well-diferentiated liposarcoma:
  • De-differentiated liposarcoma
  • Myxoid-round cell liposarcoma (MRCLS)
  • Pleomorphic liposarcoma
  • Liposarcoma, not otherwise specified

References

  1. Weiss, Sharon (1994). Histological typing of soft tissue tumours. Berlin New York: Springer-Verlag. ISBN 3540567941.
  2. Dei Tos AP (2000). “Liposarcoma: new entities and evolving concepts”. Ann Diagn Pathol. 4 (4): 252–66. doi:10.1053/adpa.2000.8133. PMID 10982304.
  3. 3.0 3.1 “WHO Classification of Soft Tissue Tumors” (PDF). WHO. WHO. Retrieved Sep 25 2014. Check date values in: |accessdate= (help)}}


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