Liposarcoma other diagnostic studies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Li-Fraumeni syndrome is the most common disease associated with liposarcoma. Genetic testing of TP53 mutation can help in the evaluation of liposarcoma.

• A number of genetic conditions are associated with liposarcoma.
• Li-Fraumeni syndrome is the most common disease associated with it.^[1]
• Mutations in the the genes TP53 that encodes the tumor suppressor protein p53, cause Li-Fraumeni syndrome.
• Genetic testing of TP53 mutation can help in the evaluation of liposarcoma.

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