Low cholesterol causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]

Overview

Low cholesterol level can be caused by various factors, with malabsorption and malnutrition being the most common. Genetic, metabolic, liver disease, and drug side effect were also reported to cause low cholesterol level.

Causes

Life Threatening Causes

Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. Low cholesterol in itself is not a life threatening condition.

Common Causes

Causes by Organ System

Cardiovascular	Shock
Chemical/Poisoning	No underlying causes
Dental	No underlying causes
Dermatologic	No underlying causes
Drug Side Effect	Levothyroxine, statins
Ear Nose Throat	No underlying causes
Endocrine	Adrenal insufficiency, hyperthyroidism, levothyroxine
Environmental	No underlying causes
Gastroenterologic	Failure to thrive, liver disease, malabsorption
Genetic	Abetalipoproteinemia , apo A-I deficiency, familial alphalipoprotein deficiency, hypobetalipoproteinemia , Smith-Lemli-Opitz syndrome
Hematologic	Beta thalassemia,^[1]^[2] leukemia^[3]
Iatrogenic	No underlying causes
Infectious Disease	Shock
Musculoskeletal/Orthopedic	No underlying causes
Neurologic	Apo A-I deficiency
Nutritional/Metabolic	Cachexia, celiac disease, failure to thrive, hyperthyroidism, malabsorption , malnutrition, Smith-Lemli-Opitz syndrome
Obstetric/Gynecologic	No underlying causes
Oncologic	Leukemia^[3]
Ophthalmologic	No underlying causes
Overdose/Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	No underlying causes
Renal/Electrolyte	Manganese deficiency
Rheumatology/Immunology/Allergy	Celiac disease
Sexual	No underlying causes
Trauma	No underlying causes
Urologic	No underlying causes
Miscellaneous	No underlying causes

Causes in Alphabetical Order

References

↑ ^1.0 ^1.1 Tassiopoulos T, Stamatelos G, Zakopoulos N, Fessas P, Eliopoulos GD (1995). “Low incidence of acute myocardial infarction in beta-thalassaemia trait carriers”. Haematologia (Budap). 26 (4): 199–203. PMID 7590514.
↑ ^2.0 ^2.1 Maioli M, Pettinato S, Cherchi GM, Giraudi D, Pacifico A, Pupita G; et al. (1989). “Plasma lipids in beta-thalassemia minor”. Atherosclerosis. 75 (2–3): 245–8. PMID 2712866.
↑ ^3.0 ^3.1 ^3.2 Pandolfino J, Hakimian D, Rademaker AW, Tallman MS (1997). “Hypocholesterolemia in hairy cell leukemia: a marker for proliferative activity”. Am J Hematol. 55 (3): 129–33. PMID 9256291.

Template:WikiDoc Sources

[pmid7590514-1] 1.0 ^1.1 Tassiopoulos T, Stamatelos G, Zakopoulos N, Fessas P, Eliopoulos GD (1995). “Low incidence of acute myocardial infarction in beta-thalassaemia trait carriers”. Haematologia (Budap). 26 (4): 199–203. PMID 7590514.

[pmid2712866-2] 2.0 ^2.1 Maioli M, Pettinato S, Cherchi GM, Giraudi D, Pacifico A, Pupita G; et al. (1989). “Plasma lipids in beta-thalassemia minor”. Atherosclerosis. 75 (2–3): 245–8. PMID 2712866.

[pmid9256291-3] 3.0 ^3.1 ^3.2 Pandolfino J, Hakimian D, Rademaker AW, Tallman MS (1997). “Hypocholesterolemia in hairy cell leukemia: a marker for proliferative activity”. Am J Hematol. 55 (3): 129–33. PMID 9256291.

[1]

[2]

[3]