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Mallory-Weiss syndrome medical therapy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamed Diab, MD [2]

Overview

Treatment of Mallory-Weiss syndrome is usually supportive because persistent bleeding is uncommon. Injection of epinephrine or cauterization may be done to stop bleeding during endoscopy.

Medical Therapy

  • Treatment of Mallory-Weiss syndrome is usually supportive because persistent bleeding is uncommon. Injection of epinephrine[1] or cauterization may be done to stop bleeding during endoscopy.
  • In rare cases, embolization of the arteries supplying the region may be needed to stop the bleeding. If all methods fail, high gastrostomy can be done to ligate the bleeding vessel.
  • Inhibitors of gastric secretion (PPI) can be given
  • Antiemetics (eg, metoclopramide) are reserved for patients with persistent vomiting.

References

  1. Gawrieh S, Shaker R (2005). “Treatment of actively bleeding Mallory-Weiss syndrome: epinephrine injection or band ligation?”. Current gastroenterology reports. 7 (3): 175. PMID 15913474.


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