Mallory-Weiss syndrome natural history, complications and prognosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamed Diab, MD [2]

Mallory-Weiss tears heal quickly in the absence of portal hypertensive. Repeated bleeding is uncommon and the outcome is usually good. Cirrhosis of the liver and problems with blood clotting make future bleeding episodes more likely to occur.

Mallory-Weiss tears heal quickly in the absence of portal hypertensive. Patients should be assessed for hemodynamic stability and determine the need for fluid resuscitation and/or blood transfusion.

• Hemorrhage
• Organ ischemia and infarction

• Repeated bleeding is uncommon and the outcome is usually good. Cirrhosis of the liver and problems with blood clotting make future bleeding episodes more likely to occur.

• Patients do not require repeat endoscopic evaluation to document healing.
• Approximately 40% to 70% of patients with bleeding Mallory-Weiss syndrome require blood transfusions.^[1][2]
• The mortality rate is approximately 5% and depends on the age and the presence of coexisting medical conditions.

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