Mast cell leukemia natural history, complications, and prognosis
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]
Overview
If left untreated, patients with mast cell leukemia may progress to develop weight loss, ascites, and bone abnormalities.Common complications of mast cell leukemia include hepatosplenomegaly, lymphadenopathy, and osteoporosis.[1] Prognosis is generally poor, and the median survival time is less than six months.[2]
Natural History, Complications, and Prognosis
If left untreated, patients with mast cell leukemia may progress to develop weight loss, ascites, and bone abnormalities.Common complications of mast cell leukemia include hepatosplenomegaly, lymphadenopathy, and osteoporosis.[1] Prognosis is generally poor, and the median survival time is less than six months.[2]
References
- ↑ 1.0 1.1 Joris, Magalie; Georgin-Lavialle, Sophie; Chandesris, Marie-Olivia; Lhermitte, Ludovic; Claisse, Jean-François; Canioni, Danielle; Hanssens, Katia; Damaj, Gandhi; Hermine, Olivier; Hamidou, Mohammed (2012). “Mast Cell Leukaemia: c-KIT Mutations Are Not Always Positive”. Case Reports in Hematology. 2012: 1–6. doi:10.1155/2012/517546. ISSN 2090-6560.
- ↑ 2.0 2.1 Georgin-Lavialle, S.; Lhermitte, L.; Dubreuil, P.; Chandesris, M.-O.; Hermine, O.; Damaj, G. (2012). “Mast cell leukemia”. Blood. 121 (8): 1285–1295. doi:10.1182/blood-2012-07-442400. ISSN 0006-4971.
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