Megacolon other imaging findings

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Colonic marker transit studies are useful to distinguish colonic inertia from functional outlet obstruction etiologies. In this test, the patient swallows a water soluble bolus of radio-opaque contrast and films are obtained 1, 3 and 5 hours later. Patients with colonic inertia show the marker spread the large intestines, while patients with outlet obstruction exhibit show accumulations of markers in some places.

A colonoscopy can also be used to rule out mechanical obstructive causes.

Anorectal manometry may help to differentiate acquired from congenital forms.

Rectal biopsy is recommended to make a final diagnosis of Hirschsprung disease.

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