Melanoma MRI

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.; Serge Korjian M.D.

Overview

MRI can be useful in the staging of brain and liver metastases. Brain MRI may be considered for the diagnosis of metastatic lesions in patients who have been diagnosed with stage IA-IV melanoma and for secondary prevention of melanoma in patients who were previously diagnosed with stage IIB-IV melanoma (annually for 5 years).

MRI can be useful in the staging of brain and liver metastases.^[1]^[2]
Malignant melonoma on MRI can present as an enhancing mass with low to intermediate signal intensity and a high-signal intensity.^[3]
MRI can also show regional lymphadenopathy in malignant melanoma.^[3]
Brain MRI is recommended for the diagnosis of metastatic lesions in the following conditions:^[4]

In patients who have been diagnosed with stage IA-IV melanoma
For secondary prevention of melanoma in patients who were previously diagnosed with stage IIB-IV melanoma (annually for 5 years)

↑ Perng, Powell; Marcus, Charles; Subramaniam, Rathan M. (2015). “18F-FDG PET/CT and Melanoma: Staging, Immune Modulation and Mutation-Targeted Therapy Assessment, and Prognosis”. American Journal of Roentgenology. 205 (2): 259–270. doi:10.2214/AJR.14.13575. ISSN 0361-803X.
↑ Nanni, C.; Fantini, L.; Nicolini, S.; Fanti, S. (2010). “Non FDG PET”. Clinical Radiology. 65 (7): 536–548. doi:10.1016/j.crad.2010.03.012. ISSN 0009-9260.
↑ ^3.0 ^3.1 Ogura I, Sasaki Y, Kameta A, Sue M, Oda T (2017). “A Rare Case of Malignant Melanoma of the Mandible:  CT and MRI Findings”. Chin J Dent Res. 20 (2): 111–114. doi:10.3290/j.cjdr.a38276. PMID 28573265.
↑ Coit DG, Andtbacka R, Anker CJ, Bichakjian CK, Carson WE, Daud A; et al. (2013). “Melanoma, version 2.2013: featured updates to the NCCN guidelines”. J Natl Compr Canc Netw. 11 (4): 395–407. PMID 23584343.