Mental retardation medical therapy
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Chelsea Mae Nobleza, M.D.[2]
Overview
Some confirmed etiologies for intellectual disabilities can be prevented with different treatment modalities such as enzyme supplementation or chelation in cases of Wilson’s disease. Symptomatic treatment is also instituted in cases of seizures in tuberous sclerosis.
Medical Therapy
Medical intervention for identified causes of intellectual disability should be instituted. [1]
- Replacement of deficient molecules
- Thyroxine supplementation for congenital hypothyroidism
- Enzyme replacement therapy
- Copper histidine for Menkes disease
- Small molecule therapy
- Pyridoxine, Vitamin B12, and folate for homocystinuria
- Low phenylalanine diet for phenylketonuria
- Vigabatrin for tuberous sclerosis
- Chelation in cases of Wilson disease
References
- ↑ Kishore MT, Udipi GA, Seshadri SP (January 2019). “Clinical Practice Guidelines for Assessment and Management of intellectual disability”. Indian J Psychiatry. 61 (Suppl 2): 194–210. doi:10.4103/psychiatry.IndianJPsychiatry_507_18. PMC 6345136. PMID 30745696.
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