Microangiopathic hemolytic anemia causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mydah Sajid, MD[2]

Microangiopathic hemolytic anemia is a clinical manifestation of a large number of diseases. The gentic mutations make some patients prone to microangiopathic hemolytic anemia.

The most important causes are^[1]:

• Aortic Stenosis (most common cause of MAHA)
• Thrombotic thrombocytopenic purpura (TTP)
• Hemolytic uremic syndrome (HUS)
• Disseminated intravascular coagulation (DIC)
• Drug Side Effect- Cyclosporine
• HELLP syndrome and eclampsia
• Heparin-induced thrombocytopenia (HIT)
• Severe glomerulonephritis
• Several other rare causes

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