Mirizzi's syndrome overview

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Mirizzi’s syndrome is an uncommon clinical condition caused by the compression of common hepatic duct due to impaction of gallstone in the cystic duct or neck of the gallbladder. This results in acquired obstructive jaundice, which could be due to direct extrinsic compression of the bile duct or fibrosis caused by chronic cholecystitis (inflammation). The chronic inflammation and ulceration may also result in cholecystobiliary fistula or cholecystoenteric fistula. ERCP is the gold standard for diagnosis, however, ultrasonography, CT scan and MRCP are commonly done. Surgical management is the mainstay treatment for Mirizzi’s syndrome.