Mixed connective tissue disease history and symptoms

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[2]

Patients with MCTD may have a positive history of raynaud’s phenomen, arthralgia, gastroesophageal reflux, myalgia and dyspnea. Common symptoms of MCTD include swollen fingers (“sausage digits”), diffuse swelling of hands, and dry cough. Less common symptoms include rashes, alopecia, mild fever, fatigue.

Patients with MCTD may have a positive history of:^[1][2]

• Raynaud’s phenomen
• Arthralgia
• Gastroesophageal reflux
• Myalgia
• Dyspnea

Common symptoms of MCTD include:^[3][4]

• Swollen fingers (sausage digits)
• Diffuse swelling of hands
• Dry cough

Less common symptoms of MCTD include:^[1]

• Rashes
• Alopecia
• Mild fever
• Fatigue

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