Molsidomine

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Molsidomine is an orally active, long acting vasodilating drug. Molsidomine is metabolized in the liver to the active metabolite SIN-1. SIN-1 is an unstable compound that releases nitric oxide upon decay as the actual vasodilating compound.

Molsidomine as well as SIN-1 are sydnone imines, a class of mesoionic heterocyclic aromatic chemical compounds.

• Nitric oxide
• Vasodilator