Monoclonal gammopathy of undetermined significance other imaging findings

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Omer Kamal, M.D.[2]

Overview

99mTc-Sestamibi and PET/CT may be helpful in the diagnosis of MGUS. 99mTc-Sestamibi show increased mitochondrial activity and findings on PET/CT may show early involvement of bone marrow.

Other Imaging Findings

99mTc-Sestamibi and PET/CT may be helpful in the diagnosis of MGUS. 99mTc-Sestamibi show incresaed mitochondial activity and findings on PET/CT may show early involvement of bone marrow.^[1] PET/CT is also commonly performed to assess for osseous lesions, as PET/CT is very sensitive for bone breakdown.

References

↑ Mena E, Choyke P, Tan E, Landgren O, Kurdziel K (January 2011). “Molecular imaging in myeloma precursor disease”. Semin. Hematol. 48 (1): 22–31. doi:10.1053/j.seminhematol.2010.11.006. PMC 3023940. PMID 21232655.

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[pmid21232655-1] Mena E, Choyke P, Tan E, Landgren O, Kurdziel K (January 2011). “Molecular imaging in myeloma precursor disease”. Semin. Hematol. 48 (1): 22–31. doi:10.1053/j.seminhematol.2010.11.006. PMC 3023940. PMID 21232655.

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