Motile sperm domain containing 3
Motile sperm domain containing 3 is a protein that in humans is encoded by the MOSPD3 gene.[1]
Function
This gene encodes a multi-pass membrane protein with a major sperm protein (MSP) domain. The deletion of a similar mouse gene is associated with defective cardiac development and neonatal lethality. Alternate transcriptional splice variants, encoding different isoforms, have been described.
References
Further reading
- Glöckner G, Scherer S, Schattevoy R, Boright A, Weber J, Tsui LC, Rosenthal A (October 1998). “Large-scale sequencing of two regions in human chromosome 7q22: analysis of 650 kb of genomic sequence around the EPO and CUTL1 loci reveals 17 genes”. Genome Research. 8 (10): 1060–73. doi:10.1101/gr.8.10.1060. PMC 310788. PMID 9799793.
- Pall GS, Wallis J, Axton R, Brownstein DG, Gautier P, Buerger K, Mulford C, Mullins JJ, Forrester LM (December 2004). “A novel transmembrane MSP-containing protein that plays a role in right ventricle development”. Genomics. 84 (6): 1051–9. doi:10.1016/j.ygeno.2004.08.017. PMID 15533722.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
© 2026 MyEClinic – IFTM Institut für Telematik in der Medizin GmbH