Mucinous cystadenocarcinoma biopsy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Qurrat-ul-ain Abid, M.D.[2], Ammu Susheela, M.D. [3]

On microscopic histopathological analysis, mucinous differentiation, nuclear atypia, and necrosis are characteristic findings of mucinous cystadenocarcinoma.

• Features:

• Mucinous differentiation
• Tall columnar cells in glands with apical mucin
• May have an endocervical-like or intestinal-like appearance
• Invasive morphology
• Back-to-back glands/confluent growth pattern
• Desmoplastic stromal response
• Cribriforming of glands
• Infiltration the tumor capsule^[1]

• Malignant characteristics:

• Nuclear atypia
• Necrosis
• No cilia

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