Multiple cutaneous leiomyoma

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Multiple cutaneous leiomyomas, also known as Pilar leiomyomas,^[1] arise from the arrectores pilorum muscles, and are made up of a poorly circumscribed proliferation of haphazardly arranged smooth muscle fibers located in the dermis that appear to infiltrate the surrounding tissue and may extend into the subcutis.^[1]

Sometimes associated with uterine leiomyomas (a combination known as multiple cutaneous and uterine leiomyomatosis, MCUL), these lesions may also be a manifestation of the hereditary leiomyomatosis and renal cell cancer syndrome.

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  Multiple cutaneous leiomyoma. Adapted from Dermatology Atlas.^[2]
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  Multiple cutaneous leiomyoma. Adapted from Dermatology Atlas.^[2]
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  Multiple cutaneous leiomyoma. Adapted from Dermatology Atlas.^[2]
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  Multiple cutaneous leiomyoma. Adapted from Dermatology Atlas.^[2]
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  Multiple cutaneous leiomyoma. Adapted from Dermatology Atlas.^[2]
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  Multiple cutaneous leiomyoma. Adapted from Dermatology Atlas.^[2]
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  Multiple cutaneous leiomyoma. Adapted from Dermatology Atlas.^[2]
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  Multiple cutaneous leiomyoma. Adapted from Dermatology Atlas.^[2]
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  Multiple cutaneous leiomyoma. Adapted from Dermatology Atlas.^[2]
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  Multiple cutaneous leiomyoma. Adapted from Dermatology Atlas.^[2]

• List of cutaneous conditions

• “Hereditary multiple cutaneous leiomyomatosis” at Atlas of Genetics and Cytogenetics in Oncology and Haematology

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