Mycoplasma pneumonia medical therapy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Antimicrobial therapy is the mainstay of therapy for atypical pneumonia caused by Mycoplasma. Pharmacologic therapies for Mycoplasma pneumonia include either a macrolide (e.g. azithromycin) for 2-5 days, doxycycline for 14 days, or a fluoroquinolone for 14 days. Supportive therapy includes rest, adequate fluid intake, and administration of either non-steroidal anti-inflammatory drugs (NSAIDS) or acetaminophen if needed. Aspirin should be avoided among children.

Medical Therapy

Supportive Care

Supportive therapy includes rest, adequate fluid intake, and administration of either nonsteroidal anti-inflammatory drugs (NSAIDS) or acetaminophen if needed.
Aspirin should be avoided among children.

Antimicrobial Regimen

All patients diagnosed with Mycoplasma pneumonia are treated with antimicrobial therapy.

1. Atypical pneumonia^[1]^[2]

Preferred regimen (1): Azithromycin 500 mg PO qd on day 1 and 250 mg PO qd on days 2 to 5
Preferred regimen (2): Clarithromycin 500 mg PO qd for 14 days
Preferred regimen (3): Moxifloxacin 400 mg PO qd for 14 days
Preferred regimen (4): Levofloxacin 750 mg PO qd for 14 days
Alternative regimen : Doxycycline 100 mg PO bid for 14 days

References

↑ Bennett, John (2015). Mandell, Douglas, and Bennett’s principles and practice of infectious diseases. Philadelphia, PA: Elsevier/Saunders. ISBN 978-1455748013.
↑ Bartlett, John (2012). Johns Hopkins ABX guide : diagnosis and treatment of infectious diseases. Burlington, MA: Jones and Bartlett Learning. ISBN 978-1449625580.

[1] Bennett, John (2015). Mandell, Douglas, and Bennett’s principles and practice of infectious diseases. Philadelphia, PA: Elsevier/Saunders. ISBN 978-1455748013.

[2] Bartlett, John (2012). Johns Hopkins ABX guide : diagnosis and treatment of infectious diseases. Burlington, MA: Jones and Bartlett Learning. ISBN 978-1449625580.

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