Myeloproliferative neoplasm physical examination

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2] Shyam Patel [3]

Patients with myeloproliferative neoplasm are usually well-appearing. Physical examination of patients with chronic myelogenous leukemia is usually remarkable for skin bruising, fever, splenomegaly, and lymphadenopathy.

Common physical examination findings associated with myeloproliferative neoplasm include:^[1][2][3][4]

• Patients are usually well-appearing at an early time point in the disease and ill-appearing at a later time point in the disease.

• Fever
• Tachycardia

• Ecchymoses
• Petechiae
• Ulcers
• Vesicles
• Pallor

• Decreased vision acuity
• Mucosal pallor

• Lymphadenopathy

• Vesicular breath sounds
• Wheezing

• Axillary lymphadenopathy (usually painless)

• Splenomegaly
• Hepatomegaly
• Tenderness to palpation

• Inguinal lymphadenopathy (usually painless)
• Scrotal swelling
• Priapism

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