Myocardial rupture pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Overview

The most common cause of myocardial rupture is a recent myocardial infarction, with the rupture typically occurring three to five days after infarction. Other causes of rupture include cardiac trauma, endocarditis (infection of the heart),^[1]^[2] cardiac tumors, infiltrative diseases of the heart,^[1] and aortic dissection.

Pathophysiology

Images shown below are courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology

Myocardial Rupture of the Free Wall

Gross horizontal section of ruptured anterolateral infarct
Gross, Acute MI, external view of ruptured myocardial infarction near apex

Myocardial rupture
Myocardial rupture

Myocardial rupture
Myocardial rupture

Myocardial rupture
Myocardial rupture

Myocardial rupture: Gun shot

Ventricular Septal Rupture

Heart, Acute MI, Ventricular septum rupture at posterior wall.

Gross; acute myocardial infarction with ventricular septal rupture

Acute MI, rupture of the ventricular septum. A close up view.

References

↑ ^1.0 ^1.1 Lin TH, Su HM, Voon WC, Lai HM, Yen HW, Lai WT, Sheu SH. (2006). “Association between hypertension and primary mitral chordae tendinae rupture”. Am J Hypertens. 19 (1): 75–9. PMID 16461195.
↑ de Diego C, Marcos-Alberca P, Pai RK. (2006). “Giant periprosthetic vegetation associated with pseudoaneurysmal-like rupture” (PDF). Eur Heart J. 27 (8): 912. PMID 16569654.

Template:WikiDoc Sources

[Lin-2006-1] 1.0 ^1.1 Lin TH, Su HM, Voon WC, Lai HM, Yen HW, Lai WT, Sheu SH. (2006). “Association between hypertension and primary mitral chordae tendinae rupture”. Am J Hypertens. 19 (1): 75–9. PMID 16461195.

[de_Diego-2006-2] Diego C, Marcos-Alberca P, Pai RK. (2006). “Giant periprosthetic vegetation associated with pseudoaneurysmal-like rupture” (PDF). Eur Heart J. 27 (8): 912. PMID 16569654.

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