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Negative predictive value

Assistant Editor(s)-In-Chief: Kristin Feeney, B.S.

Overview

The negative predictive value is the proportion of individuals without preclinical disease who test negative using the specified testing modality.

Worked example

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Definition

The Negative Predictive Value can be defined as:[1]

<math> NPV = \frac{\rm number\ of\ True\ Negatives}{{\rm number\ of\ True\ Negatives}+{\rm number\ of\ False\ Negatives}}</math>

or, alternatively,

<math> NPV = \frac{({\rm specficity}) ({\rm 1 – prevalence})}{({\rm specificity}) ({\rm 1 – prevalence}) + (1 – {\rm sensitivity}) ({\rm prevalence})} </math>

References

  1. Altman DG, Bland JM (1994). “Diagnostic Tests 2 – Predictive Values”. British Medical Journal. 309 (6947): 102. Unknown parameter |month= ignored (help)

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