Nephrotic syndrome historical perspective

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Ali Poyan Mehr, M.D. [2] Associate Editor(s)-in-Chief: Mehrian Jafarizade, M.D [3]

Overview

In 1484, Cornelus Roelans of Belgium described a child with “whole body swelling” and nephropathy. In 1905, Müller described the term of “nephrosis” for non-inflammatory kidney diseases.

Historical Perspective

In 1484, Cornelus Roelans of Belgium described a child with “whole body swelling” and nephropathy.
In 1722, Theodore Zwinger of Basel described nephrotic syndrome in children, with decreased urine output due to “obstruction and compression of the tubules of the kidney.”
In 1827, Richard Bright described the triad of generalized edema, proteinuria, and kidney disease, as features of nephrotic syndrome.
In 1905, Müller described the term of “nephrosis” for non-inflammatory kidney diseases.^[1]

References

↑ Pal A, Kaskel F (2016). “History of Nephrotic Syndrome and Evolution of its Treatment”. Front Pediatr. 4: 56. doi:10.3389/fped.2016.00056. PMC 4885377. PMID 27303658.

[pmid27303658-1] Pal A, Kaskel F (2016). “History of Nephrotic Syndrome and Evolution of its Treatment”. Front Pediatr. 4: 56. doi:10.3389/fped.2016.00056. PMC 4885377. PMID 27303658.

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