Neuroblastoma classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Zahir Ali Shaikh, MD [2]

Overview

International neuroblastoma pathology classification system is used for the classification of neuroblastic tumors. It is subdivided in 02 main categories based on the morphologic features of neuroblastic tumors into; schwannian stroma-poor and schwannian stroma-rich/dominant.

Classification

International neuroblastoma pathology classification, a system based on the framework of Shimada classification with minor modifications is proposed for international use in classification of neuroblastic tumors. ^[1]^[2]^[3]
It is a biologically relevant and pathologically significant classification system based on the morphologic features of neuroblastic tumors,i-e,neuroblastoma, ganglioneuroblastoma and ganglioneuroma.^[4]^[5]

Neuroblastic tumors

Schwannian stroma-poor group

Schwannian stroma-rich/dominant group

Undifferentiated neuroblastoma
Poorly differentiated neuroblastoma
Differentiating neuroblastoma

Nodular ganglioneuroblastoma
Intermixed ganglioneuroblastoma
Maturing ganglioneuroma
Mature ganglioneuroma

References

↑ Neuroblastoma, Ganglioneuroblastoma and Ganglioneuroma. Stanford Medicine Surgical Pathology Criteria(2015) http://surgpathcriteria.stanford.edu/srbc/neuroblastoma-ganglioneuroblastoma-ganglioneuroma/ Accessed on October, 5 2015
↑ Shimada H, Umehara S, Monobe Y, Hachitanda Y, Nakagawa A, Goto S; et al. (2001). “International neuroblastoma pathology classification for prognostic evaluation of patients with peripheral neuroblastic tumors: a report from the Children’s Cancer Group”. Cancer. 92 (9): 2451–61. PMID 11745303.
↑ Shimada, Hiroyuki; Ambros, Inge M.; Dehner, Louis P.; Hata, Jun-ichi; Joshi, Vijay V.; Roald, Borghild; Stram, Daniel O.; Gerbing, Robert B.; Lukens, John N.; Matthay, Katherine K.; Castleberry, Robert P. (1999). “The International Neuroblastoma Pathology Classification (the Shimada system)”. Cancer. 86 (2): 364–372. doi:10.1002/(SICI)1097-0142(19990715)86:2<364::AID-CNCR21>3.0.CO;2-7. ISSN 0008-543X.
↑ H. Shimada, I. M. Ambros, L. P. Dehner, J. Hata, V. V. Joshi, B. Roald, D. O. Stram, R. B. Gerbing, J. N. Lukens, K. K. Matthay & R. P. Castleberry (1999). “The International Neuroblastoma Pathology Classification (the Shimada system)”. Cancer. 86 (2): 364–372. PMID 10421273. Unknown parameter |month= ignored (help)
↑ H. Shimada, I. M. Ambros, L. P. Dehner, J. Hata, V. V. Joshi & B. Roald (1999). “Terminology and morphologic criteria of neuroblastic tumors: recommendations by the International Neuroblastoma Pathology Committee”. Cancer. 86 (2): 349–363. PMID 10421272. Unknown parameter |month= ignored (help)

Template:WikiDoc Sources

[Stanford-1] Neuroblastoma, Ganglioneuroblastoma and Ganglioneuroma. Stanford Medicine Surgical Pathology Criteria(2015) http://surgpathcriteria.stanford.edu/srbc/neuroblastoma-ganglioneuroblastoma-ganglioneuroma/ Accessed on October, 5 2015

[pmid11745303-2] Shimada H, Umehara S, Monobe Y, Hachitanda Y, Nakagawa A, Goto S; et al. (2001). “International neuroblastoma pathology classification for prognostic evaluation of patients with peripheral neuroblastic tumors: a report from the Children’s Cancer Group”. Cancer. 92 (9): 2451–61. PMID 11745303.

[ShimadaAmbros1999-3] Shimada, Hiroyuki; Ambros, Inge M.; Dehner, Louis P.; Hata, Jun-ichi; Joshi, Vijay V.; Roald, Borghild; Stram, Daniel O.; Gerbing, Robert B.; Lukens, John N.; Matthay, Katherine K.; Castleberry, Robert P. (1999). “The International Neuroblastoma Pathology Classification (the Shimada system)”. Cancer. 86 (2): 364–372. doi:10.1002/(SICI)1097-0142(19990715)86:2<364::AID-CNCR21>3.0.CO;2-7. ISSN 0008-543X.

[4] H. Shimada, I. M. Ambros, L. P. Dehner, J. Hata, V. V. Joshi, B. Roald, D. O. Stram, R. B. Gerbing, J. N. Lukens, K. K. Matthay & R. P. Castleberry (1999). “The International Neuroblastoma Pathology Classification (the Shimada system)”. Cancer. 86 (2): 364–372. PMID 10421273. Unknown parameter |month= ignored (help)

[5] H. Shimada, I. M. Ambros, L. P. Dehner, J. Hata, V. V. Joshi & B. Roald (1999). “Terminology and morphologic criteria of neuroblastic tumors: recommendations by the International Neuroblastoma Pathology Committee”. Cancer. 86 (2): 349–363. PMID 10421272. Unknown parameter |month= ignored (help)

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