Neurosyphilis other imaging findings

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]

Overview

Other imaging findings of neurosyphilis include novel PET/CT technology, multimodal ophthalmologic imaging and bone scintigraphy. In PET/CT scan, increased FDG uptake in lymph nodes may be seen. Multimodal ophthalmologic imaging combines ophthalmoscopy with spectral domain optical coherence tomography (SD-OCT) to produce high definition imaging of the posterior chamber of the eye. Bone scintigraphy allows clinicians to visualize bone uptake of Technetium-99 (T-99m) using x-ray technology.

Other imaging studies

Other imaging findings of neurosyphilis include novel PET/CT technology, multimodal ophthalmologic imaging and bone scintigraphy.

PET/CT (FDG Uptake)

Increased FDG uptake in lymph nodes is seen.^[1]

Bone Scintigraphy

Heterogenous uptake of T-99m in bone scintigraphy.^[2]

Multimodal Ophthalmologic Imaging

Multifocal lesions ^[3]^[4]
Retinal precipitates^[3]
Unilateral yellow lesions^[3]
Nodular elevations of the choroid^[4]

References

↑ Kim JM, Lee SM, Bae SB, Lee JS, Kim SY (2016). “The role of PET/CT in diagnosing generalized lymphadenopathy in asymptomatic secondary syphilis”. Hell J Nucl Med. 19 (1): 60–2. doi:10.1967/s002449910340. PMID 26929943.
↑ Naraghi AM, Salonen DC, Bloom JA, Becker EJ (2010). “Magnetic resonance imaging features of osseous manifestations of early acquired syphilis”. Skeletal Radiol. 39 (3): 305–9. doi:10.1007/s00256-009-0806-7. PMID 19795120.
↑ ^3.0 ^3.1 ^3.2 Curi AL, Sarraf D, Cunningham ET (2015). “MULTIMODAL IMAGING OF SYPHILITIC MULTIFOCAL RETINITIS”. Retin Cases Brief Rep. 9 (4): 277–80. doi:10.1097/ICB.0000000000000186. PMID 26237137.
↑ ^4.0 ^4.1 Sekine Y, Yashiro S, O’hira A, Yoshida N, Morinaga M, Nagashima N; et al. (2015). “[Multimodal imaging of a case of acute syphilitic posterior placoid chorioretinitis]”. Nippon Ganka Gakkai Zasshi. 119 (4): 266–72. PMID 25980046.

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[pmid26929943-1] Kim JM, Lee SM, Bae SB, Lee JS, Kim SY (2016). “The role of PET/CT in diagnosing generalized lymphadenopathy in asymptomatic secondary syphilis”. Hell J Nucl Med. 19 (1): 60–2. doi:10.1967/s002449910340. PMID 26929943.

[pmid19795120-2] Naraghi AM, Salonen DC, Bloom JA, Becker EJ (2010). “Magnetic resonance imaging features of osseous manifestations of early acquired syphilis”. Skeletal Radiol. 39 (3): 305–9. doi:10.1007/s00256-009-0806-7. PMID 19795120.

[pmid26237137-3] 3.0 ^3.1 ^3.2 Curi AL, Sarraf D, Cunningham ET (2015). “MULTIMODAL IMAGING OF SYPHILITIC MULTIFOCAL RETINITIS”. Retin Cases Brief Rep. 9 (4): 277–80. doi:10.1097/ICB.0000000000000186. PMID 26237137.

[pmid25980046-4] 4.0 ^4.1 Sekine Y, Yashiro S, O’hira A, Yoshida N, Morinaga M, Nagashima N; et al. (2015). “[Multimodal imaging of a case of acute syphilitic posterior placoid chorioretinitis]”. Nippon Ganka Gakkai Zasshi. 119 (4): 266–72. PMID 25980046.

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