Non-bacterial thrombotic endocarditis classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aisha Adigun, B.Sc., M.D.[2]

Overview

According to Allen and Sirota, non-bacterial thrombotic endocarditis may be classified according to morphology into 5 subtypes

According to Allen and Sirota,^[1] ^[2] Non-bacterial thrombotic endocarditis may be classified according to morphology into 5 subtypes:

Allen and Sirota macroscopic classification of NBTE
Type of NBTE	Features
Type 1	Small < 3 mm Univerrucal Firmly attached to the valve
Type 2	Large > 3 mm Univerrucal Adherent to the valve
Type 3	Small 1 – 3 mm Multiverrucal Friable
Type 4	Large > 3 mm Multiverrucal Friable
Type 5	“Healed-type” Similar in consistency to the attached valve

↑ Allen AC, Sirota JH (November 1944). “The Morphogenesis and Significance of Degenerative Verrucal Endocardiosis (Terminal Endocarditis, Endocarditis Simplex, Nonbacterial Thrombotic Endocarditis)”. Am. J. Pathol. 20 (6): 1025–55. PMC 2033063. PMID 19970792.
↑ Sanjay Asopa, Anish Patel, Omar A. Khan, Rajan Sharma, Sunil K. Ohri, Non-bacterial thrombotic endocarditis, European Journal of Cardio-Thoracic Surgery, Volume 32, Issue 5, November 2007, Pages 696–701, https://doi.org/10.1016/j.ejcts.2007.07.029