Noncompaction cardiomyopathy thromboembolism

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Patients with NCC are at risk of thromboembolic events including stroke, transient ischemic attacks and mesenteric ischemia/infarction.

Pathophysiology

Patients with NCC are at risk of embolization becuase of the stasis that occurs as a result of left ventricular dysfunction and atrial fibrillation, and the abnormal eddying that occurs because of trabeculation of the ventricle.

Incidence

While embolic events do not occur among children, among adutls, the incidence of ischemic events ranges from 21% to 38% ^[1]^[2].

References

↑ Ritter M, Oechslin E, Sutsch G, et al. Isolated noncompaction of the myocardium in adults. Mayo Clin Proc. 1997; 72: 26–31.
↑ Oechslin EN, Attenhofer Jost CH, Rojas JR, et al. Long-term follow-up of 34 adults with isolated left ventricular noncompaction: a distinct cardiomyopathy with poor prognosis. J Am Coll Cardiol. 2000; 36: 493–500.

[1] Ritter M, Oechslin E, Sutsch G, et al. Isolated noncompaction of the myocardium in adults. Mayo Clin Proc. 1997; 72: 26–31.

[2] Oechslin EN, Attenhofer Jost CH, Rojas JR, et al. Long-term follow-up of 34 adults with isolated left ventricular noncompaction: a distinct cardiomyopathy with poor prognosis. J Am Coll Cardiol. 2000; 36: 493–500.

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