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Ogilvie syndrome natural history, complications and prognosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

If left untreated, of patients with acute colonic pseudo-obstruction may progress to develop intestinal perforation which is life threatening complication. Common complications of Ogilvie’s syndrome include colonic ischemia and intestinal perforation. Prognosis of Ogilvie syndrome depends on the underlying cause of pseudo-obstruction.

Natural History, Complications, and Prognosis

Natural History

  • If left untreated, of patients with acute colonic pseudo-obstruction may progress to develop intestinal perforation which is life threatening complication.

Complications

Prognosis

  • Prognosis of Ogilvie syndrome depends on the underlying cause of the pseudoobstruction and the developed complications.[1]
  • Prognosis is generally poor with mortatlity rate is estimated to be 15% with early treatment.
  • The mortality rate is 36-44% in case the colonic ischemia or intestinal perforation develop.

References

  1. Saunders MD, Kimmey MB (2005). “Systematic review: acute colonic pseudo-obstruction”. Aliment Pharmacol Ther. 22 (10): 917–25. doi:10.1111/j.1365-2036.2005.02668.x. PMID 16268965.

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