Oxyfedrine

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Oxyfedrine is a vasodilator. Oxyfedrine was found to depress the tonicity of coronary vessels, improve myocardial metabolism (so that heart can sustain hypoxia better) and also exert a positive chronotropic and inotrophic effects, thereby not precipitating angina pectoris. The latter property (positive chronotropic and inotrophic effects) is particularly important, because other vasodilators used in angina may be counter productive causing coronary steal phenomenon.

Synergestic effects with antibiotics have been suggested.^[1]

References

↑ Mazumdar, Kaushiki (2005-04). “In vitro and in vivo synergism between tetracycline and the cardiovascular agent oxyfedrine HCl against common bacterial strains”. Biological & Pharmaceutical Bulletin. 28 (4): 713–717. ISSN 0918-6158. PMID 15802815. Unknown parameter |coauthors= ignored (help); Check date values in: |date= (help)

[1] Mazumdar, Kaushiki (2005-04). “In vitro and in vivo synergism between tetracycline and the cardiovascular agent oxyfedrine HCl against common bacterial strains”. Biological & Pharmaceutical Bulletin. 28 (4): 713–717. ISSN 0918-6158. PMID 15802815. Unknown parameter |coauthors= ignored (help); Check date values in: |date= (help)

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