POEMS syndrome risk factors

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2]

The most potent risk factor leading to the development of POEMS syndrome is multiple myeloma of osteosclerotic type.

The most potent risk factor leading to the development of POEMS syndrome is multiple myeloma of osteosclerotic type. Other risk factors include the following:

• Castleman’s disease
• Monoclonal gammopathy of undetermined significance (MGUS)
• Plasmacytoma

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