PTBP2

Polypyrimidine tract binding protein 2, also known as PTBP2, is a protein which in humans is encoded by the PTBP2 gene.^[1]^[2]

Function

The protein encoded by this gene binds to the intronic cluster of RNA regulatory elements, downstream control sequence (DCS). It is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract-binding protein PTBP1 but it is expressed primarily in the brain.^[2]

References

↑ Markovtsov V, Nikolic JM, Goldman JA, Turck CW, Chou MY, Black DL (October 2000). “Cooperative assembly of an hnRNP complex induced by a tissue-specific homolog of polypyrimidine tract binding protein”. Mol. Cell. Biol. 20 (20): 7463–79. doi:10.1128/MCB.20.20.7463-7479.2000. PMC 86300. PMID 11003644.
↑ ^2.0 ^2.1 “Entrez Gene: PTBP2 polypyrimidine tract binding protein 2”.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

[pmid11003644-1] Markovtsov V, Nikolic JM, Goldman JA, Turck CW, Chou MY, Black DL (October 2000). “Cooperative assembly of an hnRNP complex induced by a tissue-specific homolog of polypyrimidine tract binding protein”. Mol. Cell. Biol. 20 (20): 7463–79. doi:10.1128/MCB.20.20.7463-7479.2000. PMC 86300. PMID 11003644.

[entrez-2] 2.0 ^2.1 “Entrez Gene: PTBP2 polypyrimidine tract binding protein 2”.

[1]

[2]