PYGO2
Pygopus homolog 2 is a protein that in humans is encoded by the PYGO2 gene.[1][2]
References
- ↑ Thompson B, Townsley F, Rosin-Arbesfeld R, Musisi H, Bienz M (May 2002). “A new nuclear component of the Wnt signalling pathway”. Nat Cell Biol. 4 (5): 367–73. doi:10.1038/ncb786. PMID 11988739.
- ↑ “Entrez Gene: PYGO2 pygopus homolog 2 (Drosophila)”.
Further reading
- Kramps T, Peter O, Brunner E, et al. (2002). “Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex”. Cell. 109 (1): 47–60. doi:10.1016/S0092-8674(02)00679-7. PMID 11955446.
- Pilvar P, Chalbatani GM, Forghanifard MM, Mahmoodzadeh H, Besanjideh P (2017). “The evaluation of SALL4 gene silencing, and effects on PYGO2, twist and maml genes in esophageal squamous cell carcinoma”. Int J Pharm Sci Res. 8 (7): 1000–07. doi:10.13040/IJPSR.0975-8232.8(7).1000-07.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Townsley FM, Thompson B, Bienz M (2004). “Pygopus residues required for its binding to Legless are critical for transcription and development”. J. Biol. Chem. 279 (7): 5177–83. doi:10.1074/jbc.M309722200. PMID 14612447.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). “Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Brandenberger R, Wei H, Zhang S, et al. (2005). “Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation”. Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). “The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Wan D, Gong Y, Qin W, et al. (2004). “Large-scale cDNA transfection screening for genes related to cancer development and progression”. Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. doi:10.1073/pnas.0404089101. PMC 524842. PMID 15498874.
- Popadiuk CM, Xiong J, Wells MG, et al. (2006). “Antisense suppression of pygopus2 results in growth arrest of epithelial ovarian cancer”. Clin. Cancer Res. 12 (7 Pt 1): 2216–23. doi:10.1158/1078-0432.CCR-05-2433. PMID 16609037.
- Beausoleil SA, Villén J, Gerber SA, et al. (2006). “A probability-based approach for high-throughput protein phosphorylation analysis and site localization”. Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.
- Hoffmans R, Basler K (2007). “BCL9-2 binds Arm/beta-catenin in a Tyr142-independent manner and requires Pygopus for its function in Wg/Wnt signaling”. Mech. Dev. 124 (1): 59–67. doi:10.1016/j.mod.2006.09.006. PMID 17113272.
- Andrews PG, Lake BB, Popadiuk C, Kao KR (2007). “Requirement of Pygopus 2 in breast cancer”. Int. J. Oncol. 30 (2): 357–63. doi:10.3892/ijo.30.2.357. PMID 17203217.
© 2026 MyEClinic – IFTM Institut für Telematik in der Medizin GmbH