Palmar plantar erythrodysesthesia risk factors

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mandana Chitsazan, M.D. [2]

The most common and established risk factors are chemotherapeutic agents. The severity of the condition depends on the dose and frequency of the agent.

• Exposure to chemotherapeutic agents has been proven to be an established risk factor.
• It has a direct relation with the dose of and duration of exposure to chemotherapeutic agents.
• The data is limited to support any other associated risk factors as the pathophysiology of palmar plantar erythrodysesthesia.