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Papilledema differential diagnosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Kalsang Dolma, M.B.B.S.[2]

Overview

Papilledema should be distinguished from pseudopapilledema

Differentiating of Papilledema from other Diseases

Papilledema should be distinguished from pseudopapilledema which is caused by

  • Optic disc drusen:[1] These are globules of mucoproteins and mucopolysaccharides that progressively calcify. They are thought to be the remnants of the axonal transport system of degenerated retinal ganglion cells. Optic disc drusen have also been referred to as congenitally elevated or anomalous discs, pseudopapilledema, pseudoneuritis, buried disc drusen, optic nerve head drusen and disc hyaline bodies. Ophthalmoscopy and B-scan ocular ultrasonography allow appropriate diagnosis of optic disc drusen, which mimics papilledema.[2]This is important to avoid unnecessary interventions and anxiety

References

  1. Sahin A, Cingü AK, Ari S, Cinar Y, Caça I (2012). “Bilateral optic disc drusen mimicking papilledema”. J Clin Neurol. 8 (2): 151–4. doi:10.3988/jcn.2012.8.2.151. PMC 3391621. PMID 22787500. Unknown parameter |month= ignored (help)
  2. Khonsari RH, Wegener M, Leruez S, Cochereau I, Milea D (2010). “[Optic disc drusen or true papilledema?]”. Rev. Neurol. (Paris) (in French). 166 (1): 32–8. doi:10.1016/j.neurol.2009.05.003. PMID 19540541. Unknown parameter |month= ignored (help)

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