Parathyroid cancer epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

The incidence of parathyroid cancer is approximately 0.015 per 100,000 individuals in United States. Parathyroid cancer affects men and women equally.

• In developed countries, the prevalence of parathyroid cancer in United States is estimated to be 0.005%.

• In developed countries, the incidence of parathyroid cancer is 0.015 per 100,000 individuals.

• The incidence of parathyroid cancer increases with age; the median age at diagnosis is between 45 and 51 years.

• The female to male ratio is 1:1.

• In the United States, Europe, and Japan, parathyroid carcinoma has been estimated to cause hyperparathyroidism (HPT) in 0.017% to 5.2% of the cases; however, many series report this entity to account for less than 1% of patients with primary hyperparathyroidism.^[1]

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