Parotitis historical perspective

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.

Overview

Parotitis was first discovered by Hippocrates in the 5th century B.C.E. Claude D. Johnson M.D. and Ernest W. Goodpasture M.D. discovered the mumps virus, the most common cause of parotitis. The mumps virus was first isolated in 1945 by K. Habel and John Enders, leading to the first clinical trials to develop vaccinations. The mumps vaccine was developed by Maurice Hilleman and colleagues in December 1967, immunizing against the most common parotitis cause.

Discovery

Parotitis was first described by Hippocrates in the 5th century B.C.E.^[1]
- The discovery was made by observations of swelling of the parotid glands and the testicles.^[2]
In 1934, Claude D. Johnson M.D. and Ernest W. Goodpasture M.D. discovered the mumps virus, the most common cause of parotitis.^[1]
- They determined that the mumps virus was transferred by saliva transmission.^[3]

Landmark Events in the Development of Treatment Strategies

The mumps virus was first isolated in 1945 by K. Habel and John Enders.^[4]
- This led to the first clinical trials to develop vaccinations.
The mumps vaccine was developed by Maurice Hilleman and colleagues in December 1967, immunizing against the most common parotitis cause.

References

↑ ^1.0 ^1.1 “www.cdc.gov” (PDF).
↑ Conly J, Johnston B (2007). “Is mumps making a comeback?”. Can J Infect Dis Med Microbiol. 18 (1): 7–9. PMC 2542890. PMID 18923686.
↑ Johnson CD, Goodpasture EW (1934). “AN INVESTIGATION OF THE ETIOLOGY OF MUMPS”. J. Exp. Med. 59 (1): 1–19. PMC 2132344. PMID 19870227.
↑ Hajj Hussein I, Chams N, Chams S, El Sayegh S, Badran R, Raad M, Gerges-Geagea A, Leone A, Jurjus A (2015). “Vaccines Through Centuries: Major Cornerstones of Global Health”. Front Public Health. 3: 269. doi:10.3389/fpubh.2015.00269. PMC 4659912. PMID 26636066.

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[urlwww.cdc.gov-1] 1.0 ^1.1 “www.cdc.gov” (PDF).

[pmid18923686-2] Conly J, Johnston B (2007). “Is mumps making a comeback?”. Can J Infect Dis Med Microbiol. 18 (1): 7–9. PMC 2542890. PMID 18923686.

[pmid19870227-3] Johnson CD, Goodpasture EW (1934). “AN INVESTIGATION OF THE ETIOLOGY OF MUMPS”. J. Exp. Med. 59 (1): 1–19. PMC 2132344. PMID 19870227.

[pmid26636066-4] Hajj Hussein I, Chams N, Chams S, El Sayegh S, Badran R, Raad M, Gerges-Geagea A, Leone A, Jurjus A (2015). “Vaccines Through Centuries: Major Cornerstones of Global Health”. Front Public Health. 3: 269. doi:10.3389/fpubh.2015.00269. PMC 4659912. PMID 26636066.

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