Pelvic inflammatory disease laboratory findings

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Seyedmahdi Pahlavani, M.D. [2]

There is no specific laboratory findings for PID. Elevated ESR and CRP are suggestive for diagnosis but are not specific. NAAT must be performed to confirm the presence of N. gonorrhoeae and/or C. trachomatis.

• There is no specific laboratory findings for PID. Elevated CRP and ESR are non specific findings. Leukocytosis is another findings.
• Laboratory confirmation of Chlamydia, Gonorrhea and/or Mycoplasma genitalium in cervical discharge is helpful to guide treatment.^[1]
• All patients with suspected pelvic inflammatory disease should undergo cervical or vaginal nucleic acid amplification tests for N. gonorrhoeae and C. trachomatis infection.^[2]
• Vaginal fluid should be evaluated for increased numbers of white cells (more than one neutrophil per epithelial cell) and signs of bacterial vaginosis.^[2]
• Pregnancy test should be routinely requested to help rule out ectopic pregnancy.
• Serologic testing for human immunodeficiency virus (HIV) should be performed.^[2]

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