Perflenapent
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Perflenapent (INN/USAN), or perfluoropentane (PFP), is a fluorocarbon. It has several biomedical applications including: propellant for pressurized metered dose inhalers;[2] gas core in microbubble ultrasound contrast agents;[3] and occlusion therapy via the conversion of nanometer liquid droplets into micrometer sized gas microbubbles (acoustic droplet vaporization).[4]
References
- ↑ “Perfluoropentane”. Retrieved January 14, 2013.
- ↑ Rogueda, P. G. A. HPFP, a Model Propellant for pMDIs. Drug Dev. Ind. Phar. 2003, 29, 39
- ↑ Liu, Y., Miyoshi, H., and Nakamura, M. Encapsulated ultrasound microbubbles: Therapeutic application in drug/gene delivery. J. Controlled Release 2006, 114, 89− 99
- ↑ D. Bardin, T. D. Martz, P. S. Sheeran, R. Shih, P. A. Dayton, and A. P. Lee, “High-speed, clinical-scale microfluidic generation of stable phase-change droplets for gas embolotherapy,” Lab on a Chip, vol. 11, no. 23, p. 3990, 2011.
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