Peutz-Jeghers syndrome medical therapy
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hamid Qazi, MD, BSc [2]
Overview
There is no medical treatment for Peutz-Jeghers syndrome. Depending on the associated cancer, radiotherapy or chemotherapy may be considered.
Medical Therapy
There is no medical treatment for Peutz-Jeghers syndrome. Depending on the associated cancer, radiotherapy or chemotherapy may be considered.
Patients with Peutz-Jeghers syndrome are treated with intra-operative enteroscopy (IOE) and double balloon enteroscopy (DBE).[1]
- Intra-operative enteroscopy
- Laparotomy (laparoscopy) with endoscopy is done.
- Best modality for diagnostic and therapeutic procedure of the small bowel.
- Double balloon enteroscopy
- Allows examination and treatment of the jejenum and ileum.
- Chemoprophylaxis
- Proven efficacy of rapamycin for Peutz-Jeghers syndrome in a mouse model.
References
- ↑ Kopacova, Marcela; Tacheci, Ilja; Rejchrt, Stanislav; Bures, Jan (2009). “Peutz-Jeghers syndrome: Diagnostic and therapeuticapproach”. World Journal of Gastroenterology. 15 (43): 5397. doi:10.3748/wjg.15.5397. ISSN 1007-9327.
© 2026 MyEClinic – IFTM Institut für Telematik in der Medizin GmbH