Pneumocystis jirovecii pneumonia primary prevention

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

In immunocompromised patients (e.g. cancer patients on chemotherapy, or persons living with AIDS with a CD4+ T-cell count below 200/μl), prophylaxis with co-trimoxazole or regular pentamidine inhalations may help prevent PCP. Preventive therapy is recommended for:

• Patients with AIDS who have CD4 counts below 200
• Bone marrow transplant recipients
• Organ transplant recipients
• People who take long-term, high-dose corticosteroids
• People who have had previous episodes of this infection

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