Premature atrial contraction medical therapy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Mugilan Poongkunran M.B.B.S [2]

No therapy is required for premature atrial contraction in asymptomatic individuals. If necessary, medical therapy should begin with a beta blocker.

• Most patients with PACs are asymptomatic and hence require no treatment.
• Beta blockers can reduce the symptoms related to PACs and may reduce their frequency. However, the response to beta blockers is inconsistent and variable.
• Class IA, class IC, and class III antiarrhythmic agents are considered if premature atrial contractions precipitate or trigger other supraventricular arrhythmias including atrial fibrillation and atrial flutter.

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