Primary biliary cirrhosis causes
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aravind Reddy Kothagadi M.B.B.S[2]
Overview
The cause of primary biliary cirrhosis has not been identified. However, it is thought that hyper-functioning immune system attributed to genetic predisposition is thought to have a role in causing primary biliary cirrhosis. Few environmental factors such as cigarette smoking, infections and chemical exposure have also known to play a role in causing primary biliary cirrhosis.
Causes
- The cause of primary biliary cirrhosis has not been identified. However, it is thought that hyper-functioning immune system attributed to genetic predisposition is thought to have a role in causing primary biliary cirrhosis.[1][2][3]
- Few environmental factors such as cigarette smoking, infections and chemical exposure are also known to play a role in causing primary biliary cirrhosis.[1][2][3]
- To learn more about the risk factors for the development of primary biliary cirrhosis, click here.
References
- ↑ 1.0 1.1 Carey EJ, Ali AH, Lindor KD (2015). “Primary biliary cirrhosis”. Lancet. 386 (10003): 1565–75. doi:10.1016/S0140-6736(15)00154-3. PMID 26364546.
- ↑ 2.0 2.1 Selmi C, Bowlus CL, Gershwin ME, Coppel RL (2011). “Primary biliary cirrhosis”. Lancet. 377 (9777): 1600–9. doi:10.1016/S0140-6736(10)61965-4. PMID 21529926.
- ↑ 3.0 3.1 Juran BD, Lazaridis KN (2014). “Environmental factors in primary biliary cirrhosis”. Semin Liver Dis. 34 (3): 265–72. doi:10.1055/s-0034-1383726. PMC 4232304. PMID 25057950.
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