Primary biliary cirrhosis historical perspective
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aysha Anwar, M.B.B.S[2], Anmol Pitliya, M.B.B.S. M.D.[3]
Overview
In 1851, Addison and Gull first described the clinical picture of progressive obstructive jaundice in the absence of mechanical obstruction of the large bile ducts. Ahrens et al in 1950, coined the term primary biliary cirrhosis for this disease. In 1986, the association between primary biliary cirrhosis and anti-mitochondrial antibodies was first reported.
Historical Perspective
Discovery
- In 1851, Addison and Gull first described primary biliary cirrhosis in the Guys hospital report titled as “On a Certain Affectation of the Skin Vitiligoiidea-alpha plana, beta tuberosa”.[1]
- In 1950, Ahrens et al. coined the term “primary biliary cirrhosis.[2]
- In 1956, Walker et al first described the association between anti-mitochondrial antibodies and primary biliary cirrhosis.[3]
- In 1986, the association between primary biliary cirrhosis and anti-mitochondrial antibodies was first reported.[4]
References
- ↑ Cheung AC, Montano-Loza A, Swain M, Vincent C, Renner E, Sherman M; et al. (2015). “Time to make the change from ‘primary biliary cirrhosis’ to ‘primary biliary cholangitis‘“. Can J Gastroenterol Hepatol. 29 (6): 293. PMC 4578449. PMID 26196152.
- ↑ AHRENS EH, PAYNE MA, KUNKEL HG, EISENMENGER WJ, BLONDHEIM SH (1950). “Primary biliary cirrhosis”. Medicine (Baltimore). 29 (4): 299–364. PMID 14796348.
- ↑ WALKER JG, DONIACH D, ROITT IM, SHERLOCK S (1965). “SEROLOGICAL TESTS IN DIAGNOSIS OF PRIMARY BILIARY CIRRHOSIS”. Lancet. 1 (7390): 827–31. PMID 14263538.
- ↑ Mitchison HC, Bassendine MF, Hendrick A; et al. (1986). “Positive antimitochondrial antibody but normal alkaline phosphatase: is this primary biliary cirrhosis?”. Hepatology. 6 (6): 1279–84. doi:10.1002/hep.1840060609. PMID 3793004.
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