Health Dictionary Find a Doctor

Primary mediastinal large B-cell lymphoma epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Badria Munir M.B.B.S.[2]

Overview

Primary mediastinal large B-cell lymphoma represents 4% of overall non-hodgkins lymphomas and affects females predominantly.

Epidemiology and Demographics

Age

  • The incidence of primary mediastinal large B-cell lymphoma increases with age; the median age at diagnosis is 35 years.[2]

Gender

  • Females are more commonly affected with primary mediastinal large B-cell lymphoma than males.[2]

References

  1. “A clinical evaluation of the International Lymphoma Study Group classification of non-Hodgkin’s lymphoma. The Non-Hodgkin’s Lymphoma Classification Project”. Blood. 89 (11): 3909–18. June 1997. PMID 9166827.
  2. 2.0 2.1 Nguyen LN, Ha CS, Hess M, Romaguera JE, Manning JT, Cabanillas F, Cox JD (July 2000). “The outcome of combined-modality treatments for stage I and II primary large B-cell lymphoma of the mediastinum”. Int. J. Radiat. Oncol. Biol. Phys. 47 (5): 1281–5. PMID 10889382.

© 2026 MyEClinic – IFTM Institut für Telematik in der Medizin GmbH