Primary sclerosing cholangitis other diagnostic studies
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]
Overview
A liver biopsy may be performed in patients with primary sclerosing cholangitis, although it is not necessary for diagnosis. The pathognomonic finding of periductal onion-skin fibrosis is rarely seen. However, a liver biopsy may be useful when the small ducts subtype of the primary sclerosing cholangitis or that associated with autoimmune hepatitis are suspected.
Other Diagnostic Studies
Liver Biopsy
A liver biopsy may be performed in patients with primary sclerosing cholangitis, although it is not necessary for diagnosis. The pathognomonic finding of periductal onion-skin fibrosis is rarely seen. However, a liver biopsy may be useful when the small ducts subtype of the primary sclerosing cholangitis or that associated with autoimmune hepatitis are suspected.[1][2][3]
References
- ↑ Lazaridis KN, LaRusso NF (2016). “Primary Sclerosing Cholangitis”. N. Engl. J. Med. 375 (12): 1161–70. doi:10.1056/NEJMra1506330. PMID 27653566.
- ↑ Eaton JE, Talwalkar JA, Lazaridis KN, Gores GJ, Lindor KD (2013). “Pathogenesis of primary sclerosing cholangitis and advances in diagnosis and management”. Gastroenterology. 145 (3): 521–36. doi:10.1053/j.gastro.2013.06.052. PMC 3815445. PMID 23827861.
- ↑ Lazaridis KN, LaRusso NF (2015). “The Cholangiopathies”. Mayo Clin. Proc. 90 (6): 791–800. doi:10.1016/j.mayocp.2015.03.017. PMC 4533104. PMID 25957621.
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