Prokineticin receptor

The prokineticin receptor is a G protein-coupled receptor which binds the peptide hormone prokineticin. There are two variants each encoded by a different gene (PROKR1, PROKR2).^[1] These receptors mediate gastrointestinal smooth muscle contraction and angiogenesis.

References

↑ Lin DC, Bullock CM, Ehlert FJ, Chen JL, Tian H, Zhou QY (2002). “Identification and molecular characterization of two closely related G protein-coupled receptors activated by prokineticins/endocrine gland vascular endothelial growth factor”. J. Biol. Chem. 277 (22): 19276–80. doi:10.1074/jbc.M202139200. PMID 11886876.

External links

“Prokineticin Receptors”. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology.
PROKR1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
PROKR2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

[pmid11886876-1] Lin DC, Bullock CM, Ehlert FJ, Chen JL, Tian H, Zhou QY (2002). “Identification and molecular characterization of two closely related G protein-coupled receptors activated by prokineticins/endocrine gland vascular endothelial growth factor”. J. Biol. Chem. 277 (22): 19276–80. doi:10.1074/jbc.M202139200. PMID 11886876.

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