Prolactinoma classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2], Anmol Pitliya, M.B.B.S. M.D.[3]

Overview

Prolactinoma can be classified based upon either size or local invasion. Based on size, a prolactinoma can be classified as a microprolactinoma (<10 mm diameter) or macroprolactinoma (>10 mm diameter).

Classification

Prolactinoma may be classified based on either size or local invasion.

Classification of prolactinoma
Classification basis		Type/Grade	Criteria
Classification based on size^[1]		Microprolactinoma	<10 mm diameter
Classification based on size^[1]		Macroprolactinoma	>10 mm diameter
Classificatioin based on local invasion^[2]^[3]^[4]	Size and Invasion	0	Normal pituitary appearance
		I	Enclosed within the sella turcica, microadenoma smaller than 10 mm
		II	Enclosed within the sella turcica, macroadenoma 10 mm or larger
		III	Invasive, locally, into the sella turcica
		IV	Invasive, diffusely, into the sella turcica
	Grading scheme for suprasellar extensions	A	0 to 10 mm suprasellar extension occupying the suprasellarcistern
		B	10 mm to 20 mm extension and elevation of the third ventricle
		C	20 mm to 30 mm extension occupying the anterior of the third ventricle
		D	A larger than 30 mm extension, beyond the foramen of Monro, or Grade C with lateral extensions

References

↑ Ezzat S, Asa SL, Couldwell WT, Barr CE, Dodge WE, Vance ML, McCutcheon IE (2004). “The prevalence of pituitary adenomas: a systematic review”. Cancer. 101 (3): 613–9. doi:10.1002/cncr.20412. PMID 15274075.
↑ “Pituitary Tumors Treatment (PDQ®)—Health Professional Version – National Cancer Institute”.
↑ Yeh PJ, Chen JW (1997). “Pituitary tumors: surgical and medical management”. Surg Oncol. 6 (2): 67–92. PMID 09436654.
↑ Hardy J: Transsphenoidal surgery of hypersecreting pituitary tumors. In: Kohler PO, Ross GT, eds.: Diagnosis and treatment of pituitary tumors: proceedings of a conference sponsored jointly by the National Institute of Child Health and Human Development and the National Cancer Institute, January 15-17, 1973, Bethesda, Md. Amsterdam, The Netherlands: Excerpta medica, 1973, pp 179-98

Template:WikiDoc Sources

[pmid15274075-1] Ezzat S, Asa SL, Couldwell WT, Barr CE, Dodge WE, Vance ML, McCutcheon IE (2004). “The prevalence of pituitary adenomas: a systematic review”. Cancer. 101 (3): 613–9. doi:10.1002/cncr.20412. PMID 15274075.

[urlPituitary_Tumors_Treatment_(PDQ®)—Health_Professional_Version_-_National_Cancer_Institute-2] “Pituitary Tumors Treatment (PDQ®)—Health Professional Version – National Cancer Institute”.

[pmid09436654-3] Yeh PJ, Chen JW (1997). “Pituitary tumors: surgical and medical management”. Surg Oncol. 6 (2): 67–92. PMID 09436654.

[4] Hardy J: Transsphenoidal surgery of hypersecreting pituitary tumors. In: Kohler PO, Ross GT, eds.: Diagnosis and treatment of pituitary tumors: proceedings of a conference sponsored jointly by the National Institute of Child Health and Human Development and the National Cancer Institute, January 15-17, 1973, Bethesda, Md. Amsterdam, The Netherlands: Excerpta medica, 1973, pp 179-98

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