Proerythroblast

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [2] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.

A proerythroblast (or rubriblast, or pronormoblast) is the earliest of four stages in development of the normoblast.

In histology, it is very difficult to distinguish it from the other “blast” cells (lymphoblast, myeloblast, monoblast, and megakaryoblast.) The cytoplasm is blue in an H&E stain, indicating that it is basophilic.

Some sources consider the terms “pronormoblast” and “proerythroblast” to be synonyms.^[1] However, other sources^[2] consider “proerythroblast” to be a parent term, divided into the following two categories:

• “pronormoblast” – normal develoment
• “promegaloblast” – abnormal development

• Histology image: 01804loa – Histology Learning System at Boston University – “Bone Marrow and Hemopoiesis: bone marrow smear, erythroblast series with proerythroblast”
• Template:OklahomaHistology
• Histology at KUMC blood-blood04
• Image and description at purdue.edu
• Histology of “promegaloblast” at marist.edu (pernicious anemia)
• Interactive image at usuarios.lycos.es
• Overview at temple.edu

Template:Blood

Template:Skin and subcutaneous tissue symptoms and signs Template:Nervous and musculoskeletal system symptoms and signs Template:Urinary system symptoms and signs Template:Cognition, perception, emotional state and behaviour symptoms and signs Template:Speech and voice symptoms and signs Template:General symptoms and signs

Template:SIB cs:Proerytroblast id:Rubriblas sk:Proerytroblast

Template:WikiDoc Sources