Psoriatic arthritis causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chandrakala Yannam, MD [2]

Overview

The exact etiology of psoriatic arthritis is not known. Genetics, environmental factors, and immune mechanisms act as triggers for the disease development and progression.

Causes

There are no established causes of psoriatic arthritis.
The occurrence of psoriatic arthritis is secondary to a combination of genes, immune mechanisms and exposure to specific external factors or triggers, which increase an individual’s risk of developing psoriatic arthritis.
These risk factors lead to complex interactions between the genetics, immune system, and the environment.^[1]

References

↑ Barnas JL, Ritchlin CT (November 2015). “Etiology and Pathogenesis of Psoriatic Arthritis”. Rheum. Dis. Clin. North Am. 41 (4): 643–63. doi:10.1016/j.rdc.2015.07.006. PMID 26476224.

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[pmid26476224-1] Barnas JL, Ritchlin CT (November 2015). “Etiology and Pathogenesis of Psoriatic Arthritis”. Rheum. Dis. Clin. North Am. 41 (4): 643–63. doi:10.1016/j.rdc.2015.07.006. PMID 26476224.

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