Pulmonary hypertension historical perspective
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]: Associate Editor(s)-in-Chief: José Eduardo Riceto Loyola Junior, M.D.[2]
Overview
Pulmonary hypertension was first described by Ernst von Romberg, a German physician, in 1891.
Historical Perspective
- Pulmonary hypertension was first described by Ernst von Romberg, a German physician, in 1891.
- In 1929, Werner Forssman demonstrated that it was possible to perform right-sided catheterization in humans by performing catheterization on himself.
- In 1951, Dresdale coined the term primary pulmonary hypertension after describing series of cases of this new pathology. He also investigated the effects of tolzoline in a woman with pulmonary arterial hypertension causing a sudden reduction in pulmonary vascular resistance.
- In the late 1960s, there was an epidemic of pulmonary arterial hypertension induced by aminorex, which sparked interest in the disease.
- Pulmonary hypertension was first classified into primary and secondary in 1973 during the World Health Organization (WHO) meeting on PH in Geneva, Switzerland.
- Bosentan was approved to treat pulmonary hypertension in 2001, and sildenafil was approved in 2005.[1]
References
- ↑ Barst RJ (2008). “Pulmonary hypertension: past, present and future”. Ann Thorac Med. 3 (1): 1–4. doi:10.4103/1817-1737.37832. PMC 2700428. PMID 19561874.
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