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Pyrithyldione

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Pyrithyldione (Presidon, Persedon) is a psychoactive drug invented in 1949.[1] An improved method of manufacture was patented by Roche in 1959.[2] It was used as a hypnotic or sedative and presumed to be less toxic than barbiturates.[3] Today, this substance is no longer used. Agranulocytosis was sometimes reported as adverse effect.[4][5]

See also

References

  1. ↑ PMID 18144514 (PMID 18144514)
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  2. ↑ US patent 3019230, Hinderling, R.; Lutz, A. H. & Schnider, O., “Method for the preparation of 2,4-dioxo-tetrahydropyridines”, issued 1962-01-30, assigned to Hoffmann-La Roche 
  3. ↑ Template:Cite doi
  4. ↑ PMID 10663456 (PMID 10663456)
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  5. ↑ PMID 15399031 (PMID 15399031)
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